Nurr1 Protein Is Required for N-Methyl-d-aspartic Acid (NMDA) Receptor-mediated Neuronal Survival

Regulation of N-methyl-D-aspartic acid (NMDA) receptors by metabotropic glutamate receptor 7.

Emerging evidence suggests that metabotropic glutamate receptors (mGluRs) are potential novel targets for brain disorders associated with the dysfunction of prefrontal cortex (PFC), a region critical for cognitive and emotional processes. Because N-methyl-D-aspartic acid receptor (NMDAR) dysregulation has been strongly associated with the pathophysiology of mental illnesses, we examined the pos...

N-methyl-D-aspartic acid receptor structure and function.

Paraneoplastic Anti-N-Methyl-D-Aspartic Acid Receptor Encephalitis

Effects of Protopanaxatriol-Ginsenoside Metabolites on Rat N-Methyl-D-Aspartic Acid Receptor-Mediated Ion Currents

Ginsenosides are low molecular weight glycosides found in ginseng that exhibit neuroprotective effects through inhibition of N-methyl-D-aspartic acid (NMDA) receptor channel activity. Ginsenosides, like other natural compounds, are metabolized by gastric juices and intestinal microorganisms to produce ginsenoside metabolites. However, little is known about how ginsenoside metabolites regulate N...

Childhood N-methyl-D-aspartic acid receptor (NMDAR) antibody mediated encephalitis.

also been reported in a child with late onset regression autism [ 1 ] . In this issue, Goldberg et al., report a previouslyhealthy 9-year-old girl presenting with focal non-convulsive status epilepticus (NCSE) accompanied by focal signs (right hemianopsia) and neuroimaging with cerebrospinal fl uid positivity for the NMDAR antibody. This is the fi rst report of NMDAR encephalitis presenting as ...